Assessment of Protein C and Protein S of Pregnancy Loss Victims

Main Article Content

Igwe, Chioma Ada
Adias Teddy Charles
Eze Evelyn Mgbeoma
Nwachuku Edna Ogechi

Abstract

Background: The haemostatic changes that result in thrombophilia during the pregnant state have been linked to pregnancy loss.

Objective: Assessment of Protein S, and Protein C assays in pregnancy loss victims in Abia State, South East, Nigeria.

Materials and Methods: This was a cross-sectional study involving women in their reproductive years. Study population was stratified into 3 groups and the Protein C and Protein S concentrations measured and compared among the three groups.

Results: A total of 130 apparently healthy Nigerian women of child-bearing age were enrolled in the study. The study groups consisted of 70 women who had just lost a pregnancy, 30 women                  with normally progressing pregnancy and 30 nonpregnant women. The protein C concentration for the pregnancy-loss subjects was significantly lower than that of the normal pregnancy at p ≤ 0.01 while that of Protein S showed non-significance (p > 0.05).

Conclusion: Protein C deficiency is associated with increase in pregnancy loss.

Keywords:
Pregnancy loss, protein C, protein S.

Article Details

How to Cite
Ada, I., Charles, A., Mgbeoma, E., & Ogechi, N. (2019). Assessment of Protein C and Protein S of Pregnancy Loss Victims. International Blood Research & Reviews, 9(2), 1-7. https://doi.org/10.9734/ibrr/2019/v9i230094
Section
Original Research Article