Serum Electrolytes and Red Blood Cell Membrane Potential of Hypertensive Patients

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Nwadike Constance
Nosiri Chidi Ijeoma
Eze Adindu
Onyeabo Chimaraoke
Ezekwe Ahamefula Sunday
Onyejiekwe Catherine


Serum electrolyte and red blood cell membrane potential of hypertensive patients in Owerri metropolis were investigated. A total of 50 volunteer subjects were used for the study.  Thirty (30) of the volunteer subjects were hypertensive subjects and were used as test subjects; while the remaining 20 subjects were healthy subjects with normal blood pressure used as normentensive subjects (control). Results observed showed increased red blood cell (RBC) K+ and Cl- in hypertension subjects against normentensive subjects. Apart from K+ which reduced significantly (p<0.05), other electrolyte ions of the serum increased significantly (p<0.05) in hypertensive subjects against normentensive subjects. However, Na+ and Cl- membrane potential was not significantly (p>0.05) altered in hypertensive subjects against normotensive subjects while K+ was significantly (p<0.05) altered. The observed alterations in the parameters investigated in hypertensive subjects in the present study could be as a result of a host of derangements involving electrolyte metabolism, altered membrane transport and a possible increase in membrane fragility. This study has shown the serum electrolyte and red blood cell membrane potential of hypertensive patients in Owerri metropolis.

Electrolyte, hypertensive patients, membrane potential, red blood cell.

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How to Cite
Constance, N., Ijeoma, N., Adindu, E., Chimaraoke, O., Sunday, E., & Catherine, O. (2019). Serum Electrolytes and Red Blood Cell Membrane Potential of Hypertensive Patients. International Blood Research & Reviews, 10(1), 1-7.
Original Research Article


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