Kell Blood Group Antigens Not Found in Indigenes of Ogoni Ethnic Group of Rivers State, Nigeria

Main Article Content

Serekara Gideon Christian
Evelyn Mgbeoma Eze
Anthony Chijioke Uzoanya Ezimah
Fiekumo Igbida Buseri

Abstract

Aim: The aim of the study was to determine the frequency of occurrence and percentage distribution of Kell blood group antigens in indigenes of Ogoni ethnic group of Rivers State, Nigeria.

Study Design:  This was a cross-sectional study carried out among indigenes of Ogoni whose first generational parental origin is Ogoni. A total of 101 subjects (49 females and 52 males), within the age of 30–60 years were recruited for the study and they were apparently healthy and free from transfusion transmissible infections upon serological screening.

Place and Duration of Study: Ogoniland is located in an area along the Niger Delta Eastern edge, and to the north-east of the Imo River and Port Harcourt city. Ogoniland covers about 1036 Sq Km and borders the Bay of Guinea. All participants were recruited in Bori. Bori is the traditional headquarter of Ogoni. Bori is located on latitude: 4040ʹ34.64ʺ N and longitude: 7021ʹ54.68ʺ E. The analysis was carried out at the Post Graduate Laboratory of Rivers State University, Nkpolu-Oroworukwo, Port Harcourt, Rivers State, Nigeria. Port Harcourt, the capital of Rivers State, is located on latitude 4.750N and longitude 7.000E and lies along Bonny River in the Niger Delta. All subjects were recruited the same day and their blood samples collected on 2nd October, 2019, and analysis conducted on 3rd October, 2019.

Methodology: Identification of Kell blood group antigens was done using Anti-Kell monoclonal reagent, prepared by Lorne Laboratories Ltd, UK. Lot No: 76090-A5; Expiry Date: 2021/02/21. Phenotyping of red cells was done using tube method as described by Lorne Laboratory Ltd.

Results: The result showed zero frequency of occurrence and percentage distribution of Kell blood group antigen in the studied population (49 males and 52 females).

Conclusion: The presence of Kell blood group antigens in indigenes of Ogoni recruited for the study which serve as representative of the Ogonis was rare. It is therefore necessary to take into cognizance that haemolytic transfusion reactions due to Kell antigens and antibodies will rarely occur, and as such Kell blood group is not significant in blood transfusion and in antenatal and blood group serology amongst the Ogonis.

Keywords:
Kell, blood, antigens, ogoni-indigenes, Rivers State, Nigeria.

Article Details

How to Cite
Christian, S. G., Eze, E. M., Ezimah, A. C. U., & Buseri, F. I. (2020). Kell Blood Group Antigens Not Found in Indigenes of Ogoni Ethnic Group of Rivers State, Nigeria. International Blood Research & Reviews, 11(1), 1-5. https://doi.org/10.9734/ibrr/2020/v11i130119
Section
Original Research Article

References

Denomme GA. Molecular basis of blood group expression. Transfusion and Apheresis Science. 2011;44:53–63.

Lorne Laboratories. Monoclonal blood grouping reagents: Anti-K monoclonal, Document Reference Number: CEPI760. United Kingdom: Lorne Laboratories Ltd; 2018.

Daniels GL, Anstee DJ, Cartron JP, Dahr W, Henry S, Issitt PD, Jørgensen J, Judd WJ, Kornstad L, Levene C, Lomas-Francis C, Lubenko A, Mallory D, Moulds JM, Moulds JJ, Okubo Y, Overbeeke M, Reid, ME, Rouger P, Seidl S, Sistonen P, Wendel S, Zelinski T. Blood group terminology. ISBT working party on terminology for red cell surface antigens. Vox Sanguinis. 1995;69:265-279.

Issitt PD, Anstee DJ. Applied Blood Group Serology, 4th Edition, Durham: Montgomery Scientific; 1998.

Reid ME, Lomas-Francis C. Blood Group Antigen Fact Book, 2nd edition, San Francisco: Academic; 2003.

Reid ME, Lomas-Francis C, Olsson ML. The blood group antigen factsbook, 3rd Edition, Amsterdam: Academic Press (Elsevier); 2012.

Downs T. Other blood group system. In: Quinley ED. (Eds) Immunohematology Principles and Practice, 3rd Edition, Philadelphia: Lippincott Williams & Wilkins. 2011;119-134

Reid ME, Calhoun L, Petz LO. Erythrocyte Antigen and Antibodies. In Lichtman MA, Beutler E, Kipps, TJ, Seligsohn U, Kaushansky K, Prchal JT. (Eds), Williams Haematology, 7th Edition, New York: McGraw-Hill. 2006;2119.

Oyinlade OA, Vincent, JM. The Ogoni of Nigeria. Anthropology Faculty Publications. 113.
Available:http://digitalcommons.unl.edu/anthropologyfacpub/113
[Acessed: February 5, 2020]

ENCYCLOpedia.com. Ogoni.
Available:https://www.encyclopedia.com Accessed: October 10, 2019.

Cheesbrough M. District Laboratory Practice in Tropical Countries, 2nd Edition, Part 2. Cambridge: Cambridge University Press; 2010.