Haematological Study on the Effects of Goko Cleanser (Herbal Mixture) on Adult Female Wistar Rats

Darlington Nnamdi Onyejike *

Department of Anatomy, Nnamdi Azikiwe University, Nnewi Campus, Anambra State, Nigeria.

McWilliams, Winifred Chidera

Department of Anatomy, Nnamdi Azikiwe University, Nnewi Campus, Anambra State, Nigeria.

Mmaju, Chidinma Ifeyinwa

Department of Human Physiology, Nnamdi Azikiwe University, Nnewi Campus, Anambra State, Nigeria.

Okeke, Somadina Nnamdi

Department of Anatomy, Nnamdi Azikiwe University, Nnewi Campus, Anambra State, Nigeria.

Obiesie, Ifechukwu Justicia

Department of Anatomy, Nnamdi Azikiwe University, Nnewi Campus, Anambra State, Nigeria.

Eze, Chinyere Elizabeth

Department of Anatomy, Nnamdi Azikiwe University, Nnewi Campus, Anambra State, Nigeria.

*Author to whom correspondence should be addressed.


Abstract

Introduction: Goko cleanser is one of the popular herbal mixtures used by the Nigerian populace. This study was carried out to evaluate the effects of this herbal mixture on some haematological parameters of adult female Wistar rats.

Methodology: A total of twenty five Wistar rats weighing about 160 – 280g were divided into five groups according to their corresponding weights. The groups were designated as groups 1 – 5. Group 1 served as the control group, while groups 2, 3, 4, and 5 received 1000mg/Kg, 1500mg/Kg, 2000mg/Kg and 4000mg/Kg respectively.

Results: The TWBC, PCV, PLATELET count, and RBC and Hb showed a statistically significant (p<0.05) increase for the test groups 2 – 5 when compared to the control group. The body weight had a statistically significant (p<0.05) decrease in groups 2, 4, and 5; while group 3 had a statistically insignificant (p>0.05) decrease.

Conclusion and Recommendation: This study revealed that Goko Cleanser contains some haemopoietic benefits, but inhibit appetite centres. Hence, this study recommends that further study be carried out on the effects of this herbal mixture on the brain so as to reveal the extent of its effect on the appetite centres.

Keywords: Herbal mixtures, haematological parameters, blood analyses, body-weight analysis.


How to Cite

Onyejike, D. N., Chidera, M. W., Ifeyinwa, M. C., Nnamdi, O. S., Justicia, O. I., & Elizabeth, E. C. (2021). Haematological Study on the Effects of Goko Cleanser (Herbal Mixture) on Adult Female Wistar Rats. International Blood Research & Reviews, 12(1), 8–19. https://doi.org/10.9734/ibrr/2021/v12i130141

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