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Anti Colton-A Foeto-Neonatal Haemolytic Disesase: Diagnosis; Clinical Outcome and Family Study

  •   G. Gessoni
  •   L. Collodel
  •   I. Vaccara
  •   M. Pivetta
  •   T. Mancuso
  •   P. Lago
  •   A. Cattarozzi
  •   N. Revelli
  •   A. Barzan
  •   P. Cavicchioli

International Blood Research & Reviews, Volume 14, Issue 1, Page 29-37
DOI: 10.9734/ibrr/2023/v14i1299
Published: 27 January 2023

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Abstract


The authors report a case of neonatal haemolytic disease (HDN) attributable to maternal allo immunization to a high frequency antigen present on paternal red blood cells which have been identified as Colton-a (Coa).

The case seemed worthy of reporting not only for the relative rarity of HDN from anti Coa but for the rigorous approach followed in the immunohaematological follow-up of pregnancy and for the diagnostic effort expended in identifying the specificity of the antibody. A family study of ascendants, collaterals and descendants was also carried out using genotyping techniques.

Keywords:
  • Anti-Coa
  • family study
  • genotyping
  • HDFN
  • Full Article - PDF
  • Review History

How to Cite

Gessoni, G., Collodel, L., Vaccara, I., Pivetta, M., Mancuso, T., Lago, P., Cattarozzi, A., Revelli, N., Barzan, A., & Cavicchioli, P. (2023). Anti Colton-A Foeto-Neonatal Haemolytic Disesase: Diagnosis; Clinical Outcome and Family Study. International Blood Research & Reviews, 14(1), 29–37. https://doi.org/10.9734/ibrr/2023/v14i1299
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