Transfusion Transmitable Infections and Reasons for Release of Total Blood to the Blood Bank of the Yaounde Centrall Hospital

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Chetcha C. Bernard


Blood banks in sub-Saharan Africa regularly face shortages of blood products (PS). Several factors are responsible for this, including transfusion-transmissible infections (ITT) and deficiencies in the transfusion system. This study aims to determine the prevalence and the various reasons for rejection at the blood bank of the Central Hospital of Yaoundé. We first conducted a retrospective study at the blood bank of the Central Hospital of Yaoundé for 12 months between January 01, 2014 and December 31, 2014.Secondly, we carried out a prospective study in October 2015. Five milliliters (05 ml) of venous blood were taken from each participant in a tube without anticoagulant; patient samples were stored at -24°C. A rapid screening test and ELISA were used to test for HIV, HCV, HBs and syphilis on the samples taken. Approximately 15,028 bags of whole blood were drawn in 2014, of which 3,688 bags were rejected. This equates to a rejection rate of 24.54%. Discards for non-infectious reasons represented 3.51% and rejections for infectious reasons 21.03%. During the prospective study, among those selected, there were 95.74% men and 4.26% women. The average age of the participants was 30 years. Among the 705 people in this investigation, 185 blood bags were rejected. Infectious causes represented 22.55% (Hepatitis B and C, HIV and syphilis with a respective prevalence of 9.08%, 0.71% 6.95% and 5.82%) and non-infectious causes represented 3.68 % (clots, insufficient volume of PST, hemolysis and expiration with a respective prevalence of: 1.84%, 0.71 0.14% and 0.99%).The association between rejection of blood bags and qualitative variables was assessed. There emerged a significant association between the risk of rejection of a blood bag and the type of donor; condom use, number of partners, history of STIs. At the Yaoundé Central Hospital blood bank, the reasons for rejecting blood bags are divided into two categories: Mainly infectious and non-infectious. Also, certain risk variables such as not using a condom, multiple sexual partners and a history of STIs are risk factors that can encourage rejection of blood bags.

Blood bank, Yaounde Central Hospital, infections, blood bags, blood transfusion.

Article Details

How to Cite
Bernard, C. C. (2020). Transfusion Transmitable Infections and Reasons for Release of Total Blood to the Blood Bank of the Yaounde Centrall Hospital. International Blood Research & Reviews, 11(2), 15-22.
Original Research Article


Amat-Koze, JM. HIV / AIDS infection in sub-Saharan Africa, geographic; 2003.

Andreu O. Blood donation surveillance of the infection and secure transjusal risk. (0aj Barreto, CC. Sabino, EC, Gonçalez. TT, et al. Prevalence, incidence, and residual risN of human inimunodeficiency virus among community and replacement first-time blood o in São Paulo.Braisil; 2005.

Biwole Sida M, JeatsaGapdo C, Mbangue M, Essola J, Leundji H, Dissongo J. Prevalence of Hbc antibody in Ag Hbs negative blood donors in Douala. [Research report]. Cameroon; 2015.

Cruz JR. Pérez-ROsales MD. Availability, safety, and quality of blood for transfusion in the America; 2003.

Doumbia Z. Problem of the Blood Transfusion in the Health Center of Reference de Bougouni [Thesis]. Mali: Faculty of Medicine, Pharmacy and Odonto-Stomatology; 2009.

Dupraz F. Good transfusion practices, from prescription to action: Rhone-Alpe; 2007.

Eboumbou C, Ngo Sack F, Essangui G, Mbangue M, Lehmann L. HIV, HBV, HCV and T. pallidum infections among blood donors and Transfusion-related complications among recipients at the Laquintinie hospital in Douala, Cameroon [Research report] Cameroon; 2012.

Hoofnagle J, Seeff L, Bales Z, et al. Type B hepatitis afier transfusion with blooda Bure antigen training antibody. [Research report]; 1978.

Mbanya D., Takam D., Ndumbe PM. Serological findings amongst first-time blood donors in Yaoundé: Cameroon; 2013.

Ministry of Health National Reference Laboratory-Rwanda. Standard laboratory operating procedures for anti reiroviral treatment program in Rwanda. Rwanda; 2005.

Mole S, Onana E, Biholong D. HIV and risk factors among donors family replacement blood and volunteers at central hospital in Yaoundé Cameroon. Research report]. France; 2011.

Naila A, Nasir K, Fazal L. Serprevalence of HB, HCV and HlV infection among voluntary non remunerated and replacement donors in northern Pakiton Pal now in northern Pakistan. Pakistan; 2004.

Noah noah. D, Njouom R., Bonny A. et al. HBs Antigen prevalence in biood a WHO Iransfusional safety in the world. [Study report]. Swiss and the risk of transduction of hepatitis B at the Central hospital of Yaoundé. Cameroon. Report of Research. Cameroon; 1999.

WHO. Security of the blood, Strategy of the African region. [Study report]. Swiss WHO. The cold chain for blood, Guide for the selection and acquisition of equipment and accessories. [Study report]. Swiss; 2001.

WHO, Manual of management, maintenance and use of the equipment of the diufrod chain for blood. [Study report]. Switzerland; 2008.