Bing-Neel Syndrome – A Challenging Diagnosis: Case Report

Main Article Content

Y. Davidkova
N. Simonoski
B. Spassov
G. Balatzenko
M. Guenova

Abstract

Bing-Neel syndrome is a rare neurologic complication of Waldenström’s macroglobulinemia, characterized by infiltration of the central nervous system by clonal lymphoplasmacytes. We present a rare clinical case of a patient, who one year after the diagnosis of Waldenström’s macroglobulinemia, progressed with diverse neurologic presentation and cerebrospinal fluid involvement. The diagnosis was based on magnetic resonance imaging and flow cytometry detection of clonal B-cells in the cerebrospinal fluid. Bing-Neel syndrome should be considered in patients with neurologic symptoms and a history of Waldenström’s macroglobulinemia.

Keywords:
Bing-Neel syndrome, Waldenström’s macroglobulinemia, orbital involvement, cerebrospinal fluid.

Article Details

How to Cite
Davidkova, Y., Simonoski, N., Spassov, B., Balatzenko, G., & Guenova, M. (2020). Bing-Neel Syndrome – A Challenging Diagnosis: Case Report. International Blood Research & Reviews, 11(3), 28-33. https://doi.org/10.9734/ibrr/2020/v11i330132
Section
Case Report

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