Phenotypic and Allelic Frequency of ABO and Rh (D) Blood Group among Whole Blood Donors in a Teaching Hospital of Chhattisgarh
International Blood Research & Reviews, Volume 14, Issue 3,
Page 19-26
DOI:
10.9734/ibrr/2023/v14i3309
Abstract
Background: ABO and Rh (D) blood groups are the most important in blood transfusion and are determined genetically. Although these blood groups are common to all humans, there is variation in their allelic frequency based on region and population. This study was performed to determine the allelic frequency of ABO & Rh (D) in the donor population in the Blood Center of Chhattisgarh located in Central India.
Place and Duration of Study: It is a cross-sectional study performed in the Department of Transfusion Medicine & Blood Bank of a teaching hospital from July 2021-February 2022.
Methodology: Only the accepted whole blood donors were included. ABO & Rh (D) blood grouping was performed by conventional tube technique and their allelic frequency was determined. We studied 4078 whole blood donors out of which 4055 were males and 23 were females.
Results: Phenotypic frequency of ABO blood group system was O>B>A>AB. Rh (D) positive was more prevalent than Rh (D) negative. Allele frequency of ABO system was 0.1545 for IA, 0.2351 for IB, and 0.6105 for IO. In Rh system, allele frequency of ID was 0.8441 and Id was 0.1559.
Conclusion: Phenotypic & allelic frequency of ABO & Rh (D) shows heterogeneous distribution in different parts of the world. Our study showed blood group O & allele IO as the most common. This data is of utmost importance in the planning of transfusion services, especially during a healthcare crisis in low-resource area like ours.
- Allelic frequency
- ABO
- RH
- blood group
- prevalence
- phenotye
How to Cite
References
Available:https://www.isbtweb.org/isbt-working-parties/rcibgt/blood-group-terminology.html
Sachdeva A, Kumar M, Lal P, Kumar D, Kumar S, Salhotra V. Frequency distribution of abo and rhesus blood groups among mbbs students in a hilly state of North India. Int J Recent Sci Res. 2018; 9(1):23601-23605.
Sigamani K, Gajulapalli S (April 17, 2022) An Insight Into the Distribution of Allele Frequency of ABO and Rh (D) Blood Grouping System Among Blood Donors in a Tertiary Care Hospital in Chengalpattu District of South India. Cureus 14(4): e24207. DOI 10.7759/cureus.24207.
Sidhu S, Sidhu L S. ABO blood group frequencies among the Sansis of Punjab. Coll Anthropol. 1980;4:55–58.
Enosolease ME, Bazuaye GN. distribution of abo and rh- d blood groups in the benin area of niger-delta: Implication for regional blood transfusion. Asian J Transfus Sci. 2008;2(1):3–5.
Kumar N, Kapoor A, Kalwar A, Narayan S, Singhal MK, Kumar A, Mewara A, Bardia MR. Allele frequency of ABO blood group antigen and the risk of esophageal cancer. Biomed Res Int. 2014;2014:286810.
DOI: 10.1155/2014/286810. Epub 2014 Jun 19. PMID: 25054136; PMCID: PMC4089147.
Shrivastava S, Gahine R, Kapse V. ABO, Rhesus blood group and allele frequency in and around Raipur (Chattisgarh State), India. Int J Cur Res Rev. 2015;7(17):52-58.
Swamy CM, Basavaraj PB, Kavitha GU, Shashikala P. Prevalence of ABO and Rhesus blood group among blood donors. Indian J Public Health Res Dev. 2012;3:106‑109.
Matsushita S, Imamaru T, Mizuta T, Hand M. Acquired B anti¬gen and poly agglutination in a patient with gastric cancer. Jpn J Surg. 1983;13:540-542.
Mehta AA, Mehta AA: Frequency distribution of ABO blood group and Rh factor in Bhanpur, Bhopal . Sch Acad J Biosci. 2016;4:106-109.
Kumar S, Modak PK, Ali SH, Barpanda SK, Gusain VS, Roy R. A retrospective study: ABO and Rh phenotype blood group distribution among blood donors in H.N.B. Base Hospital, Srinagar, Uttarakhand, India. J Family Med Prim Care. 2018;7:34-38.
Chandra T, Gupta A. Frequency of ABO and Rhesus blood groups in blood donors. Asian J Transfus Sci. 2012;6:52-53.
Mohroo RN, Hassan MJ, Khan S, Ahmad N, Jetley S. Distribution pattern of ABO and Rh blood group among blood donors at Hospital Blood Bank in Delhi- An initial step to evaluate preparedness to fight an epidemic. Int Arch BioMed Clin Res [Internet]. 2020Sep.30 [cited 2022;6(3): PA3-PA6. Available:https://iabcr.org/index.php/iabcr/article/view/602.
Singh A, Srivastava RK, Deogharia KS, Singh KK. Distribution of ABO and Rh types in voluntary Blood donors in Jharkhand area as a study conducted by RIMS, Ranchi. J Family Med Prim Care. 2016;5:631-636.
Nag I, Das SS: ABO and Rhesus blood groups in potential blood donors at Durgapur Steel city of the district of Burdwan, West Bengal. Asian J Transfus Sci. 2012;6:54-55.
Giri P, Yadav S, Parhar G. Frequency of ABO and Rhesus blood groups: a study from a rural tertiary care teaching hospital in India. Int J Biol Med Res. 2011;2:988-990.
Barot T, Patel D, Shah R. Distribution of ABO and rhesus (Rh) blood groups among voluntary blood donors in central Gujarat, India. International Journal of Contemporary Medical Research. 2020;7(7):G1-G3.
Kumar M, Rathore SP: Distribution of blood groups in blood donors in the blood bank, Jhalawar Hospital & Medical College Society, Jhalawar, Rajasthan. IOSR Journal of Dental and Medical Sciences. 2018;17(8):29-33.
Anushree CN, Sujatha R, Patil SB, Jaya Prakash HT. Distribution pattern of ABO grouping and Rhesus typing among blood donors: a study from a tertiary care teaching hospital blood bank of Dr. BR Ambedkar Medical College, Bangalore. Indian J Pathol Oncol. 2017;4(1):8-11.
Soonam John. Prevalence of ABO and rhesus blood groups in blood donors: a study from a tertiary care centre in South Kerala. International Journal of Contemporary Medical Research. 2017;4(11):2314-2316.
Shrestha L, Malla U, Mahotra NB. ABO and Rh blood groups and their ethnic distribution in a teaching hospital of Kathmandu, Nepal. JNMA J Nepal Med Assoc. 2013;52(190):311-315. PMID:24362652.
Rehman GU. ABO and Rh (D) blood groups distribution in Pakistan: a systematic review. Forensic Res Criminol Int J. 2020;8(6):237‒244. DOI: 10.15406/frcij.2020.08.00334.
Dipta TF, Iqbal MR, Hossain AZ, Rahman MT, Chowdhury S. distribution of phenotypic and genotypic abo and rhesus blood groups among Bangladeshi population. Ibrahim Medical College Journal. 2011;5(2):59–62.
Iyiola OA, Igunnugbemi OO, Bello OG. Gene frequencies of ABO and Rh(D) blood group alleles in Lagos, South-West Nigeria. Egyptian Journal of Medical Human Genetics. 2012;13(2):147-153.
Woldu B, Melku M, Shiferaw E, Biadgo B, Abebe M, Gelaw Y. Phenotype, Allele and Genotype Frequency of ABO and Rhesus D Blood Groups of Blood Donors at the North Gondar District Blood Bank, Northwest Ethiopia. J Blood Med. 2022;13:11-19.DOI:10.2147/JBM.S346904. PMID: 35023982; PMCID: PMC8747761.
Bashwari LA, Al-Mulhim AA, Ahmad MS, Ahmed MA. Frequency of ABO blood groups in the Eastern region of Saudi Arabia. Saudi Med J. 2001;22(11):1008-1012. PMID: 11744976.
Mollison PL, Engelfriet CP, Conteras M. The Rh blood Group system. In: blood transfusion in clinical medicine, 9th edition. oxford: blackwell scientific publication. 1993:2008–09.
Firkin F, Chesterman C, Penington D, Rush B. De Gruchy’s Clinical haematology in medical Practice. Blackwell Science Publisher, 5th Edition; 2008: 475.
Zafar M, Masud S, Malik MM, Latif MH, Noor MS, Asmatullah: Gene frequency distribution of ABO and Rh-D blood group alleles in multan division (Punjab), Pakistan. Pure Appl. Biol. 2021;10:1173-1180.
Allawati M, Al-Kalbani L , Al-Balushi T: ABO and Rh (D) phenotypes, allele frequencies and estimated genotypes in Omanis: a retrospective study from Armed Forces Hospital. JMSCR. 2021;4: 1-7.
Amin MD, Susanto D, Naher L: Distribution pattern of ABO and Rh blood groups and their allelic frequencies among different ethnic groups in Malaysia. Asian Journal of Medical Sciences. 2015;6:25-29.
El-Moghrabi HAMN, Jwieli LA, Elramli NA, Faitor FA, El-Brghty K. A comparative study of prevalence, phenotype and genotype of ABO and Rh (D) Factor among Blood Donors from the central blood bank in benghazi, libya. International Journal of Science and Research (IJSR). 2021;10(9):1068-1074.
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